invited commentary on David Oderberg's call for conscientious objection in medicine to be permitted in the UK.

The US FDA currently encourages the addition of vitamin D to milk and cereals, with the aim of reducing rickets in children and osteoporosis in adults. However, vitamin D not only regulates the expression of genes associated with calcium homeostasis, but also genes associated with cancers, autoimmune disease, and infection. It does this by controlling the activation of the vitamin D receptor (VDR), a type 1 nuclear receptor and DNA transcription factor. Molecular biology is rapidly coming to an understanding of (...) the multiplicity of roles played by the VDR, but clinical medicine is having difficulty keeping up with the pace of change. For example, the FDA recently proposed a rule change that will encourage high levels of vitamin D to be added to even more foods, so that the manufacturers can claim those foods “reduce the risk of osteoporosis”. The FDA docket does not review one single paper detailing the transcriptional activity of vitamin D, even though, on average, one new paper a day is being published on that topic. Nor do they review whether widespread supplementation with vitamin D, an immunomodulatory secosteroid, might predispose the population to immune dysfunction. This BioEssay explores how lifelong supplementation of the food chain with vitamin D might well be contributing to the current epidemics of obesity and chronic disease. BioEssays 30:173–182, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

_Peter Greenaway's Postmodern/Poststructuralist Cinema_ Edited by Paula Willoquet-Maricondi and Mary Alemany-Galway Lanham, MD: The Scarecrow Press, 2001 ISBN 0-8108-3892-3 xxviii + 360 pp.

Ediorial Content Type Journal Article Category Editorial Pages 139-140 DOI 10.1558/hrge.v17i2.139 Authors Trevor Stammers, St Mary’s University College, London Journal Human Reproduction & Genetic Ethics Online ISSN 2043-0469 Print ISSN 1028-7825 Journal Volume Volume 17 Journal Issue Volume 17, Number 2 / 2011.

There can be little doubt, at least in the Western world, that autonomy is the ruling principle in contemporary bioethics. In spite of its ‘triumph’ however, the dominance of the utilitarian concept of autonomy is being increasingly questioned. In this paper, I explore the nature of autonomy, how it came to displace the Hippocratic tradition in medicine and how different concepts of autonomy have evolved. I argue that the reduction of autonomy to ‘the exercise of personal choice’ in medicine has (...) led to a ‘tyranny of autonomy’ which can be inimical to ethical medical practice rather than conducive to it. I take the case of Kerrie Wooltorton as an illustration of how misplaced adherence to respect for patient autonomy can lead to tragic consequences. An analysis of autonomy based on the work of Rachel Haliburton is described and applied to the role of autonomy in a recent bioethical debate — that arising from Savulescu's proposal that conscientious objection by health-care professionals should not be permit.. (shrink)

Volume 25, Issue 4, December 2019, Page 293-294.

This issue provides an end of year feast with something for everyone. Browning and Veit note how, since the presence of sentience in mammals, birds and cephalopods received official scientific reco...

I suspect that most readers will, like me, be unfamiliar with the concept of chirality. Indeed I had never heard of the term before reading Dahlen’s paper proposing the completely novel concept of...

One of the insights gained from editing a journal is to see early trends in the research topics of submissions. The ethics of data management in healthcare is an issue on which we have published a...

The demand for organs prompted the first use of elective ventilation in the UK in the 1990s. Recently the shortfall in supply of organs has once again prompted calls for elective ventilation to be instituted even in patients who are not brain dead. This paper proposes that the term ‘elective’ ventilation is a misnomer and the term non-therapeutic ventilation (NTV) should be used instead. It is further argued that the practice of NTV in cases of severe stroke is unethical and (...) has the potential of causing a variety of harms to the patient, their relatives, the healthcare professionals working in transplant teams and this may result in a backlash of reductions in the number of organ donations. (shrink)

Volume 26, Issue 2, June 2020, Page 81-81.

In 2017, The New Bioethics published its first special-themed issue on the topic of personalized medicine. It proved highly popular, especially Gyawali and Sullivan’s paper ‘Economics of Can...

Covid-19 and arguments related to abortion – these two topics between them take up the majority of the pages of this issue. That the first of these should do so, is no surprise. Over two years on f...

In last June's themed issue on environmental bioethics, presciently planned in early 2019, we published in addition our very first paper on Covid-19 – a critique of the British Medical Association'...

Bioethics is not a field for the faint-hearted. Life and death decisions are both at stake and everything in between. Increasingly, before-life decisions are being taken as well and this issue comm...

Volume 26, Issue 3, September 2020, Page 195-196.

This is a must-read text for anyone interested in the ethics surrounding gene editing. The author, a professor of clinical psychology at the University of Texas and director of their Developmental...

Volume 25, Issue 1, March 2019, Page 97-100.

Editorial for issue with articles on tranhumanism, principlism, total body transplants and inter-uterine surgery for myelomeningocele.

‘There is a tide in the affairs of men.Which, taken at the flood, leads on to fortune;’Those who edit academic journals rarely seek fortune in finan...

Volume 25, Issue 2, June 2019, Page 101-102.

Volume 25, Issue 1, March 2019, Page 1-2.

Editorial on papers relating to among other infanticide and intersex.

A review of the range of articles in the summer issue of The New Bioethics.

Organ trafficking in all its various forms is an international crime which could be entirely eliminated if healthcare professionals refused to participate in or be complicit with it. Types of organ trafficking are defined and principal international declarations and resolutions concerning it are discussed. The evidence for the involvement of healthcare professionals is illustrated with examples from South Africa and China. The ways in which healthcare professionals directly or indirectly perpetuate illegal organ transplantation are then considered, including lack of awareness, (...) the paucity of both undergraduate and postgraduate education on organ trafficking, turning a blind eye, advocacy of organ commercialism, and the lure of financial gain. (shrink)

Amidst a plethora of books about human genome engineering (HGE), this one by John H Evans, a professor of sociology in the United States, stands out with its original and interesting take on how th...

Review of Arul Gawande's best seller about preparing for death.

‘This book is the record of an exploration. I am a writer, a non-specialist in a specialist's wilderness and I find my way with a writer's tools’. Just as we should never judge a book by i...

Review of book on the nature of conscience and history of development of ideas about it.

Arising from a research project from the Faraday Institute for Science and Religion in Cambridge, UK, this primer on gene editing is written by a postdoctoral researcher in the Faculty of Divinity...

Interest in the neural processes underlying decision making has led to a flurry of recent research in the fields of both moral psychology and neuroeconomics. In this paper, we first review some important findings from both disciplines, and then argue that the two fields can mutually benefit each other. A more explicit recognition of the role of values and norms will likely lead to more accurate models of decision making for neuroeconomists, whereas the tasks, insights into neural mechanisms, and mathematical (...) modeling common in neuroeconomic research offer moral psychologists the opportunity to expand their field and move beyond methodological limitations that may have hindered the field’s progress to this point. We conclude by highlighting an exciting group of recent studies that illustrate the potential of research that embraces the integrated moral/neuroeconomic approach that we suggest here. (shrink)

We provide a retrospective of 25 years of the International Conference on AI and Law, which was first held in 1987. Fifty papers have been selected from the thirteen conferences and each of them is described in a short subsection individually written by one of the 24 authors. These subsections attempt to place the paper discussed in the context of the development of AI and Law, while often offering some personal reactions and reflections. As a whole, the subsections build into (...) a history of the last quarter century of the field, and provide some insights into where it has come from, where it is now, and where it might go. (shrink)

The first issue of Artificial Intelligence and Law journal was published in 1992. This paper offers some commentaries on papers drawn from the Journal’s third decade. They indicate a major shift within Artificial Intelligence, both generally and in AI and Law: away from symbolic techniques to those based on Machine Learning approaches, especially those based on Natural Language texts rather than feature sets. Eight papers are discussed: two concern the management and use of documents available on the World Wide Web, (...) and six apply machine learning techniques to a variety of legal applications. (shrink)

This paper argues that philosophers should pay more attention to the idea of ecosystem engineering and to the scientific literature surrounding it. Ecosystem engineering is a broad but clearly delimited concept that is less subject to many of the “it encompasses too much” criticisms that philosophers have directed at niche construction . The limitations placed on the idea of ecosystem engineering point the way to a narrower idea of niche construction. Moreover, experimental studies in the ecosystem engineering literature provide detailed (...) accounts of particular empirical situations in which we cannot neglect the O term in dE /dt = g (O, E), which helps us get beyond verbal arguments and simple models purporting to show that niche construction must not be ignored as a factor in evolution. Finally, this literature demonstrates that while ecosystem engineering studies may not require us to embrace a new evolutionary process, as niche construction advocates have claimed, they do teach us that the myriad abiotic factors concealed by the abstract term ‘environment’ are often controlled in large part by organisms. (shrink)

I argue in this paper that rather than viewing John Dewey as either a historicist or a naturalist, we should see him as strange but potentially fruitful combination of both. I will demonstrate that the notion of organism-environment interaction central to Dewey’s pragmatism stems from a Hegelian approach to adaptation; his turn to biology was not necessarily a turn away from Hegel. I argue that Dewey’s account of the organism-environment relation derives from the work of Oxford Hegelians such as Edward (...) Caird and Samuel Alexander, who were attempting to reconcile evolutionary ideas with a critique of Herbert Spencer’s environmentalist account of human thought and action. This dialectical account of organism-environment interaction played a key role in Dewey’s philosophy from the 1890s to the 1940s, despite other shifts in his thinking. (shrink)